With e cigarettes, the huge variety of constantly evolving

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LONDON (Reuters) From Apple Pie to Bubbly Bubble Gum, Irish Car Bomb canada goose clearance or Martian bar from Mars!, the flavors of electronic cigarette offer something for every taste.

Canada Goose sale A customer canada goose black friday sale puffs on an e cigarette at the Henley Vaporium in New York City in this December 18, 2013 file photo. REUTERS/Mike Segar/Files

canada goose clearance Researchers have counted 7,764 varieties of adds up uk canada goose to one of many challenges from practical constraints to conflicts of buy canada goose jacket interest in working out how safe e cigs are, and Canada Goose Parka whether they help smokers quit.

Most scientists agree e cigs have potential as a stop smoking aid. They can be used with or without nicotine and are free of the thousands of toxins in conventional cigarettes. But e cigs also throw up some unusual obstacles.

canada goose clearance sale Drug firms usually test one treatment against another. With e cigarettes, the huge variety of constantly evolving products means it would be prohibitively expensive to test every flavor and vaporizer. guess many alternative products raise similar issues when they start to canada goose uk shop make health claims.

canada goose coats E cigarettes can look like ordinary smokes but are metal and plastic battery powered gadgets that heat flavored liquids into a cloud which users suck in, then exhale as dense white plumes. Invented in their present form https://www.goosefrshop.com in China about a decade ago, e cigarettes generated $4 billion to $5 billion in sales Canada Goose sale in 2014, according to Euromonitor, a market research firm.

cheap Canada Goose The gadgets themselves come in hundreds of brands and are constantly morphing, at the Canada Goose Outlet hands of both users and the small canada goose coats on sale scale distributors who sell them online.

Because they are a strange hybrid between smoking Canada Goose Coats On Sale which kills nearly 6 million people a year and stop smoking medications, e cigs rival both tobacco and pharma. Tobacco companies have responded to that threat by buying up e cig businesses, and are now funding research. Pharma firms have kept their distance.

canada goose deals The products have also opened a rift between researchers who see their goal as eliminating nicotine Canada Goose Jackets in all its forms, and others who believe it makes more sense to reduce the harm of smoking.

got people who taken a position and they looking at the evidence only in relation to the position they got, David Sweanor, an e cig enthusiast and law professor canada goose coats at the University of Ottawa, told an e cigarette symposium in London in November.

Canada Goose Jackets PHARMA BOWS OUT There are more than 2,000 papers on e cigarettes in the scholarly journals covered by the Web of Science, a database. Of those in the highest impact journals, most have been funded by public bodies. Only a few contain original research; methodological problems or potential uk canada goose outlet bias are common, scientists have found.

Last month, in an attempt to clear matters up, Bullen and other scientists in Britain and New Zealand published their assessment of the most impartial studies. Known as a Cochrane Review a study canadian goose jacket of the best science on a subject it aimed to see if e cigs canada goose can help people stop canada goose clearance sale smoking.

Canada Goose Parka The review concluded that e cigs may help smokers quit, and that there is little sign that canada goose uk black friday they hurt users.

canada goose But it found the evidence thin and data poor. Of almost 600 studies analyzed, only 13 Canada Goose Online published papers were up to the Cochrane standard. Just two were randomized controlled trials, the most rigorous test.

canadian goose jacket Big Pharma is not helping. National Institutes of Health database.

Canada Goose online For drugs firms, smoking cessation is a small business, generating $2.4 billion buy canada goose jacket cheap in sales in 2013, according to Euromonitor. That just a www.goosefrshop.com fraction of the $206 billion the industry generated in global consumer health products.

decided we not going to play (in e cigs), GlaxoSmithKline Chief Executive Andrew Witty told Reuters. consciously canada goose factory sale had a think about it but we not going to play.

VESTED INTEREST This leaves e cheap Canada Goose cigarette companies to fund their own research, giving rise to concerns over conflicts of interest.

In 2010 one European e cig distributor, Italian firm Arbi Group Srl, sponsored a significant body of work by a team at Catania University canada goose uk outlet in Sicily. National Institutes of Health (NIH).

Canada Goose Outlet the end of the day we were stuck accepting money from e cigarette owners because there was no cheap canada goose uk other way to carry out research, said Catania professor Riccardo Polosa, who designed the trial. He Canada Goose online said he had also received funding from pharma.

canada goose store That, says Charlotta Pisinger, a Danish doctor who runs stop smoking clinics, is a problem. Last October she published a review which found one in three e cigarette studies had a conflict of interest because they were funded by e cig manufacturers, pharma or tobacco, or a combination. She saw evidence of bias: must exercise the utmost caution in trusting their conclusions, she wrote.

Experienced medical researchers say industry funding to test new products is the norm.

buy canada goose jacket majority of clinical research is sponsored by the manufacturers, said David Tovey, editor in chief of the Cochrane Library, which vets Cochrane canada goose store Reviews. Another Cochrane study has found thatscientific studies sponsored by private industry generally reported greater benefits and fewer harmful side effects than studies industry did not sponsor.

buy canada goose jacket cheap STANCE E cigarette opponents are also being scrutinized for bias.

In August, the World Health Organisation recommended that smokers should be encouraged to try already approved treatments, rather than e cigs.

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